Spanish researchers built molecules that switch on in light and stand in for lost photoreceptors, reawakening the retina’s surviving circuitry in animals blinded by degeneration.
By flipping a Notch-signaling switch, researchers grew functional helper T cells from stem cells at scale — a step toward ready-made cell therapies that skip per-patient manufacturing.
Rusfertide mimics the body’s iron-regulating hormone to rein in red-blood-cell overproduction — and in a trial, most patients no longer needed regular blood draws.
The FDA expanded tirzepatide’s label to include cutting cardiovascular risk in type 2 diabetes — a first for a GIP/GLP-1 drug and a boost for the world’s top-selling medicine.
Refreshed shots from Pfizer, Moderna and Novavax are updated for the now-dominant XFG strain — but this season’s approvals come with narrower eligibility than in past years.
Michael Polansky’s Outer Bio launched with $23M and an unusual pitch: not a drug company, but an AI platform screening compounds on living human skin.
Sequencing eight Myotis bat species uncovered genetic tricks linking their famous virus tolerance to cancer resistance and longevity — clues that could inform human aging research.
Priovant’s brepocitinib is the first pill approved for the rare autoimmune disease — in a trial, more patients improved and got off steroids than on placebo.
Using Britain’s postwar sugar rationing as a natural experiment, researchers found that lower early-life sugar exposure tracked with less cancer and slower biological aging decades on — though it can’t prove cause.
The TSLP-blocking antibody met its goals in a Phase 3 eosinophilic esophagitis trial, setting up a potential third indication and a challenge to Sanofi’s Dupixent.
By deliberately removing the antibody response that can backfire against dengue, researchers built an experimental Zika vaccine that defended mice using T cells instead.
In mice with glioblastoma, engineered nanoparticles lit up tumor clusters as small as a hair’s width during surgery, then destroyed microscopic leftover cells — and every treated animal survived.