In the TRIC-I-HF trial, a minimally invasive fix for a leaky tricuspid valve cut the combined risk of death and heart-failure hospitalization by 60% — a first for the field.
A supplement combo matched a standard antibiotic course at controlling advanced periodontitis a year later — a potential way to treat gum disease without fueling antibiotic resistance.
Frequent brief “micro-awakenings” during sleep tracked with higher genetic Alzheimer’s risk in middle-aged adults — pointing to a tiny brainstem region as a possible link.
More than 90% of health systems have deployed third-party AI tools, yet fewer than half can validate them before use — leaving a governance gap that some, like UPMC, are racing to fill.
CD19 CAR-T — built to fight blood cancers — drove treatment-refractory rheumatoid arthritis into remission in a small study, with some patients drug-free for up to a year.
STAREE — the first big primary-prevention statin trial in older adults — found atorvastatin reduced cardiovascular events, though it didn’t extend disability-free survival.
In a small study where researchers supplied every meal, a ketogenic diet reduced liver fat more than Mediterranean or low-fat diets — even though all three produced similar weight loss.
The bictegravir/lenacapavir tablet gives virologically suppressed adults — including those on complex regimens — a new one-pill, once-a-day option.
The WEE1 inhibitor APR-1051 shrank tumors in some patients with gynecologic cancers in an early trial, prompting Aprea to expand testing.
Removing a protein called AHR let injured neurons switch into repair mode, improving recovery of movement and sensation in mice — and drugs that block it are already in trials for other uses.
Spanish researchers built molecules that switch on in light and stand in for lost photoreceptors, reawakening the retina’s surviving circuitry in animals blinded by degeneration.
By flipping a Notch-signaling switch, researchers grew functional helper T cells from stem cells at scale — a step toward ready-made cell therapies that skip per-patient manufacturing.