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PI3Kγ inhibition circumvents inflammation and vascular leak in SARS-CoV-2 and other infections

Twelve years ago, cancer researchers at University of California San Diego identified a molecule that helps cancer cells survive by shuttling damaging inflammatory cells into tumor tissue. In new research, they show that the same molecule does the same thing in lung tissue infected with COVID-19 – and that the molecule can be suppressed with a repurposed cancer drug.

Twelve years ago, cancer researchers at University of California San Diego identified a molecule that helps cancer cells survive by shuttling damaging inflammatory cells into tumor tissue. In new research, they show that the same molecule does the same thing in lung tissue infected with COVID-19 – and that the molecule can be suppressed with a repurposed cancer drug.

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David Miller

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