Genome-Scale CRISPRi Atlas Maps Gene Function Across Human iPSCs

A genome-scale CRISPRi atlas maps transcriptional consequences for 11,692 gene perturbations across more than 2.5 million human iPSCs. The resource reveals regulators of metabolism, pluripotency, and RNA editing—including DBR1—and provides an open-access framework for probing how gene activity shapes the pluripotent state. The post Genome-Scale CRISPRi Atlas Maps Gene Function Across Human iPSCs appeared first on GEN – Genetic Engineering…

Source: Genetic Engineering & Biotechnology News