Health
Sanofi's Lantus Insulin Pen Is in Short Supply as Demand Climbs
Not an official shortage, and patients cannot find it. The gap between those two statements is where insulin supply problems live.
Obesity
Eli Lilly to Seek FDA Approval of Retatrutide, Its Most Powerful Obesity Drug Yet
Three receptors instead of two. Around 30% weight loss in the first trial, 21–23% in patients with diabetes and heart disease — and that difference is expected.
Latest news
Research
Alzheimer's Reshapes How DNA Folds Inside Brain Cells, Single-Cell Study Finds
Short-range contacts fall, long-range contacts rise. The genome is folding differently in diseased brain cells, and folding governs which genes run.
R&D
Scribe Raises $129M in the First Gene-Editing IPO in Over Two Years
Silencing a gene without cutting it. Scribe’s bet is that reversibility beats permanence — and $129 million is a cautious vote for the sector.
Health
Colorectal Cancer Is Rising in Younger Adults — The Warning Signs Not to Ignore
One in five cases now occurs under 54, up from one in ten thirty years ago. Rectal bleeding under 50 raises the odds of diagnosis eightfold.
Health
Weight-Loss Drugs Like Ozempic and Mounjaro Linked to Hair Loss, Review Finds
Tirzepatide showed the strongest signal and produces the most weight loss. That correlation is the most likely explanation, and it is not reassuring or alarming — it is specific.
Business
You Can Now Bet on Clinical Trial Outcomes — and Pharma Insiders Are Worried
Hundreds of people in a trial can see unblinded data. A market paying out on the result gives every one of them a reason to trade on it.
R&D
Agios Scraps Sickle Cell Drug Tebapivat After Mid-Stage Disappointment
The drug was not shown to fail. It was shown not to be different enough — which in a field where a rival just succeeded is the same outcome.
Vaccines
Study Backs Testing Merck’s Ebola Vaccine Against a Second Virus Species in Congo
Nine vaccinated people caught the wrong Ebola species and all nine survived. Not proof — but an argument that the question should be tested rather than debated.
Heart Health
Coffee May Help Your Heart — Energy Drinks May Not, Heart Experts Say
Same molecule, different delivery. Coffee gives 9–21 mg per ounce; an energy shot gives 40–69 — and concentration is the whole argument.
Obesity
Novo Nordisk Sues Eli Lilly, Alleging Misleading Obesity-Drug Ads
The allegation is comparing top doses against original lower ones. Whether that is misleading depends on what a fair comparison would even look like.
R&D
Crystalys Raises $130M to Advance Its Gout Drug Through Late-Stage Trials
Approved in Japan since 2020. Crystalys bought the Western rights and $130 million to run the trials regulators here still require.