A US Shortage of Estradiol Patches Is Squeezing Menopause and Gender-Affirming Care
Surging demand for hormone therapy has outstripped supply of the transdermal patches, and the FDA is pressing manufacturers to ramp up production.
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Surging demand for hormone therapy has outstripped supply of the transdermal patches, and the FDA is pressing manufacturers to ramp up production.
AD109 — an oral drug aimed at the muscles that keep the airway open — could offer an alternative for the many people who can’t tolerate a CPAP machine.
US neurology and headache societies updated their guidance to reflect a wave of CGRP-targeting medicines — the first refresh in over a decade.
A supplement combo matched a standard antibiotic course at controlling advanced periodontitis a year later — a potential way to treat gum disease without fueling antibiotic resistance.
In a small study where researchers supplied every meal, a ketogenic diet reduced liver fat more than Mediterranean or low-fat diets — even though all three produced similar weight loss.
Using Britain’s postwar sugar rationing as a natural experiment, researchers found that lower early-life sugar exposure tracked with less cancer and slower biological aging decades on — though it can’t prove cause.
A new analysis of grocery data suggests banning soda from food-assistance benefits cut soda buying — but shoppers redirected much of the money to other sugary drinks.
A large Swedish study tracked hundreds of thousands of people and found that those who actually completed a mailed stool test were far less likely to die of colorectal cancer.
A study of 402 adults found that physical activity and controlled blood sugar in midlife were associated with better preserved thinking skills decades later.
In a six-year study of older adults, having both abdominal obesity and low vitamin D was tied to more than double the risk of death — each condition amplifying the other.
A large study of over 21,000 women found those who used estrogen-only menopausal hormone therapy had less dementia and less Alzheimer’s pathology — but it’s an association, not proof.
A French randomized trial found healthy, low-risk people over 75 who stopped their preventive statins were no worse off on death or heart events over three years — with big caveats.
A 12-week randomized study in adults with overweight found three daily servings of full-fat dairy didn’t harm cholesterol or body composition — but it was short and industry-funded.
In 340,000 UK adults, low-to-moderate wine drinking was tied to lower heart-death risk while beer and spirits were tied to higher — but it’s observational, not proof.
At very high intravenous doses, vitamin C flips from antioxidant to pro-oxidant, generating a compound that preferentially damages stressed cancer cells. It’s still experimental.
In a 170-patient, placebo-controlled study, dronabinol cut nightmare severity more than placebo — though it did not clearly reduce overall PTSD or depression.
New data add to the case that simpler two-drug therapy works as well as the standard three-drug combination for people starting HIV treatment.
A large real-world analysis eases a lingering worry — that GLP-1 weight loss weakens bones — finding lower fracture rates with semaglutide in type 2 diabetes.
New research suggests oral GLP-1 drugs like orforglipron dial down eating for pleasure — not just hunger — by acting on the brain's reward system.
In 355,000 people, higher coffee intake was linked to sharply lower risks of cirrhosis, liver cancer, and liver-related death — with decaf working too.
JAK inhibitors raise shingles risk, so timing the vaccine matters. A randomized trial found a trade-off between a stronger vaccine response and faster arthritis relief.
A new analysis explains the paradox: GLP-1 drugs are cost-effective per patient, yet the sheer number of eligible people makes broad coverage financially daunting for insurers.
Patients report hunting across pharmacies for the Lantus SoloStar pen, which Sanofi says is temporarily constrained by rising demand.
Surgeons warn that colorectal cancer is now the leading cause of cancer death in people under 50, and subtle symptoms are too often dismissed.
A 2026 systematic review finds semaglutide and tirzepatide carry a higher hair-loss signal than older GLP-1 drugs — though the shedding appears reversible.