R&D
Gates Foundation Backs Cheap Algae-Grown Omega-3 for Mothers in Poorer Countries
Spent brewer’s grain instead of refined sugar. The substrate swap is what could take algal DHA below $52 a kilogram.
Business
Hinge Health Buys Cylinder for $105M, Adding Digital Digestive Care
Nearly 70% of US counties have no gastroenterologist. That access gap, more than the clinical fit, is what a virtual-care acquisition is buying.
Latest news
Research
Zebrafish Reveal the Biology Behind a Leading Cause of Back Pain
A fish bred without one collagen gene developed a human spinal disease — and two drugs already on pharmacy shelves slowed it down.
Business
Tarsus to Buy Alkeus for Up to $800M, Betting on a Drug for a Rare Blinding Disease
A modified vitamin A that behaves normally except in the one reaction that causes the damage. Seven years of patient follow-up, and a readout still three years away.
Business
LifeMine Raises $263M to Mine Fungi for a Safer Organ-Transplant Drug
Same enzyme as cyclosporine, different binding site, and deliberately kept out of the brain. The point is not a new target — it is removing the toxicity.
Regulatory
FDA Approves Takeda’s Orzeyful, a First-in-Class Drug for Narcolepsy Type 1
Every previous narcolepsy drug fought the symptoms. This one replaces the signal the missing neurons stopped sending.
Business
Schrödinger and Bristol Myers Squibb Deepen Their AI Drug-Discovery Pact
Designing a molecule that binds is one problem. Knowing whether a chemist can actually make it is a different one — and generative AI has been bad at it.
Regulatory
FDA Approves Tudriqev, an Engineered Cancer-Killing Virus for Advanced Melanoma
Twice rejected, then approved on a 24% response rate. What changed was not the data but the standard applied to patients with nothing left.
Research
Transplanted Human Neurons Rebuilt Breathing Circuits in Injured Rats
The transplanted cells did not replace what was lost. They relayed around it — which is why a neck injury that stops breathing might be bypassed rather than repaired.
Research
How Tau Sabotages Brain-Cell Batteries — a New Clue to Alzheimer’s
Tau does not just tangle in the cell. It gets inside the mitochondria and makes the electron chain run backwards, generating the damage that makes more tau.
Business
Braveheart Bio Raises $382M in IPO for a China-Licensed Heart Drug
Founded 2024, licensed the asset from China, public by 2026 with $382 million. The speed is the story as much as the drug.
Health
A Cannabis-Derived Drug Ended PTSD Nightmares for Over a Third of Patients in a Trial
A third of patients stopped having nightmares entirely. The trial could not show the drug helped PTSD itself — and reports that as a limit, not a footnote.